Solitary Synchronous Pancreatic Metastasis from Esophageal Squamous Cell Carcinoma: A Rare Case Report

Ahmadi Somaghian, Shahram; Mirzaei, Sepideh; Aaliehpour, Asghar; Baharvand Iran Nia, Yahya

doi:10.30476/mejc.2020.86963.1379

Solitary Synchronous Pancreatic Metastasis from Esophageal Squamous Cell Carcinoma: A Rare Case Report

Document Type : Case Report(s)

Authors

Shahram Ahmadi Somaghian ¹

Sepideh Mirzaei ²

Asghar Aaliehpour ³

Yahya Baharvand Iran Nia ⁴

¹ Department of Hematology and Oncology, Lorestan University of Medical Sciences, Khorramabad, Iran

² Department of Radiotherapy, Lorestan University of Medical Sciences, Khorramabad, Iran

³ Department of Pathology, Lorestan University of Medical Sciences, Khorramabad, Iran

⁴ Department of Internal Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran

https://doi.org/10.30476/mejc.2020.86963.1379

Abstract

Pancreas is an organ that is hardly affected by metastasis from other primary cancers; also, pancreatic metastasis from esophageal squamous cell carcinoma (ESCC) is an extremely infrequent entity. Metastatic esophageal cancer has a poor prognosis and the five-year survival rate is less than 5%. Here, we described a rare case of a 78-year-old woman presented with abdominal bloating, intermittent mild nausea, and loss of appetite and weight. Esophagogastroduodenoscopy revealed ESCC in the upper part of esophagus. A mass lesion between the head and body of pancreas was detected during metastatic work-up. Endoscopic ultrasound-guided fine needle aspiration was performed, morphologic features and immunohistochemistry confirmed metastatic squamous cell carcinoma from esophagus. Definitive chemoradiotherapy with curative intent was done on both oesophageal and pancreatic lesion. Interestingly, after nine months of treatment, the patient had no issues either in esophagus or in abdomen. In conclusion, local therapy could be considered as one of the best choices to improve the overall survival in ESCC with single metastasis to pancreas.

Keywords

Definitive chemoradiotherapy

Esophagus

Pancreas neoplasm

Solitary metastasis

Radiotherapy

How to cite this article:

Ahmadi Somaghian S, Mirzaei S, Aaliehpour A, Baharvand Iran Nia Y. Solitary synchronous pancreatic metastasis from esophageal squamous cell carcinoma: A rare case report. Middle East J Cancer. 2021;12(2): 310-4. doi: 10.30476/mejc. 2020.86963.1379.