TY - JOUR ID - 47015 TI - Solitary Synchronous Pancreatic Metastasis from Esophageal Squamous Cell Carcinoma: A Rare Case Report JO - Middle East Journal of Cancer JA - MEJC LA - en SN - 2008-6709 AU - Ahmadi Somaghian, Shahram AU - Mirzaei, Sepideh AU - Aaliehpour, Asghar AU - Baharvand Iran Nia, Yahya AD - Department of Hematology and Oncology, Lorestan University of Medical Sciences, Khorramabad, Iran AD - Department of Radiotherapy, Lorestan University of Medical Sciences, Khorramabad, Iran AD - Department of Pathology, Lorestan University of Medical Sciences, Khorramabad, Iran AD - Department of Internal Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran Y1 - 2021 PY - 2021 VL - 12 IS - 2 SP - 310 EP - 314 KW - Definitive chemoradiotherapy KW - Esophagus KW - Pancreas neoplasm KW - Solitary metastasis KW - Radiotherapy DO - 10.30476/mejc.2020.86963.1379 N2 - Pancreas is an organ that is hardly affected by metastasis from other primary cancers; also, pancreatic metastasis from esophageal squamous cell carcinoma (ESCC) is an extremely infrequent entity. Metastatic esophageal cancer has a poor prognosis and the five-year survival rate is less than 5%. Here, we described a rare case of a 78-year-old woman presented with abdominal bloating, intermittent mild nausea, and loss of appetite and weight. Esophagogastroduodenoscopy revealed ESCC in the upper part of esophagus. A mass lesion between the head and body of pancreas was detected during metastatic work-up. Endoscopic ultrasound-guided fine needle aspiration was performed, morphologic features and immunohistochemistry confirmed metastatic squamous cell carcinoma from esophagus. Definitive chemoradiotherapy with curative intent was done on both oesophageal and pancreatic lesion. Interestingly, after nine months of treatment, the patient had no issues either in esophagus or in abdomen. In conclusion, local therapy could be considered as one of the best choices to improve the overall survival in ESCC with single metastasis to pancreas. UR - https://mejc.sums.ac.ir/article_47015.html L1 - https://mejc.sums.ac.ir/article_47015_d325a03b9f1bca4972f6c9f5d12c779e.pdf ER -