Middle East Journal of Cancer

Intervention of Primary Focus of Type 1 Neurofibromatosis Presenting with Melena and Gastric Hemorrhage of Unknown Origin and Nursing Care: A Case Report

Document Type : Case Report(s)

Authors

Ghobad Abanghah 1
Abdolreza Heidarizadi 2
Hamed Tavan 3

1 Department of Gastroenterology and Hematology, School of Medicine, Ilam University of Medical Sciences, Ilam, Iran

2 Department of Teneral Surgery and Advanced Laparoscopy, Surgical Department Iranian Hospital Dubai, Dubai, United Arab Emirates

3 Nursing Department, Faculty of Nursing and Midwifery, Ilam University of Medical Sciences, Ilam, Iran

https://doi.org/10.30476/mejc.2025.103050.2121
Abstract
There are four types of neurofibromatosis, with types 1 and 2 being the most prevalent among them. The disease incidence is 1 in every 3,000 births.  In the present study, we reported a patient with neurofibromatosis type 1 presenting with melanoma and gastric hemorrhage of unknown origin. A 37-year-old woman with a history of gastrointestinal bleeding and evidence of multiple retroperitoneal masses in the computed tomography scans of abdominal and pelvic cavities was admitted to our hospital. The masses were successfully removed by surgery.
In cases of bleeding with an unknown cause, especially in patients with neurofibromatosis, the possibility of small intestinal tumors, especially gastrointestinal stromal tumors, should be considered.

Highlights

Ghobad Abanghah (Google Scholar)

Hamed Tavan (Google Scholar)

 

Keywords

Hemorrhage
Neurofibromatosis
Surgery
Case report
Mortality
Subjects

How to cite this article:

Abanghah G, Heidarizadi A, Tavan H. Intervention of Primary Focus of Type 1 Neurofibromatosis Presenting with Melena and Gastric Hemorrhage of Unknown Origin and Nursing Care: A Case Report. Middle East J Cancer. 2025;16(4):372-77. doi: 10.30476/mejc.2025.103050.2121.

 

  1. Degbelo FDA, Cito G, Guendil B, Christodoulou M, Abbassi Z. Spontaneous hemothorax in a patient with von Recklinghausen's disease: A case report and review of the literature. Am J Case Rep. 2019;20:674-8. doi: 10.12659/AJCR.915810. PMID: 31076564; PMCID: PMC6543949.
  2. Jeong SC, Kim JJ, Choi SY, Kim YH, Kim IS. Successful surgical treatment of massive spontaneous hemothorax due to intrathoracic secondary degeneration of a neurofibroma from mediastinal involvement of type 1 neurofibromatosis. J Thorac Dis. 2018 Mar;10(3):E203-E206. doi: 10.21037/jtd.2018.01.170. PMID: 29707374; PMCID: PMC5906240.
  3. Neto AF, Ferreira EG Junior, de Melo Freire Golveia Silveira L, Gusmão F, Saad KR, Saad PF. Spontaneous bilateral hemothorax in neurofibromatosis type 1 due to internal thoracic artery aneurysm: Case report. Int J Surg Case Rep. 2020;68:36-38. doi: 10.1016/j.ijscr.2020.02.026. PMID: 32113169; PMCID: PMC7044636.
  4. Adil A, Koritala T, Munakomi S, Singh AK. Neurofibromatosis type 1. 2023 Aug 13. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 29083628.
  5. Rostami F, Babahaji M, Sheikhnejad F, Karimi V. The effect of the continuous care model on the adherence to the medication regimen of patients hospitalized in the psychiatric ward: A quasi-experimental study. Journal of Nursing Advances in Clinical Sciences. 2024;1(2):85-90. doi: 10.32598/JNACS.2405.1025
  6. Hajwal SK, Ayad ZM, Hanita AT, Hussein MS, Hussein SAA, Hammoud GH, et al. Patients’ knowledge of diabetic foot self-care practice: A cross-sectional study. Journal of Nursing Advances in Clinical Sciences. 2024;1(4):178-81. doi: 10.32598/JNACS.2407.1044
  7. Hsieh DT, Rohena LO. Neurofibromatosis type 1 treatment and management. [Internet] Available at: https://emedicine.medscape.com/article/1177266-treatment?form=fpf
  8. Shohani M, Tavan H. The validity and reliability of the constructs of pain management-measuring tool for incurable patients. Iranian Red Crescent Medical Journal (IRCMJ). 2024;20(9):1-4. doi: 10.5812/ircmj.62353.
Middle East Journal of Cancer
Volume 16, Issue 4
Autumn 2025
Pages 372-377

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