Document Type : Case Report(s)


1 Surgical Oncology Department, Oncology Center Mansoura University (OCMU), Mansoura, Egypt

2 Medical Oncology Department, Oncology Center Mansoura University (OCMU), Mansoura, Egypt

3 Radiology Department, Mansoura University Hospitals (MUH), Mansoura, Egypt

4 Pathology Department, Mansoura University Hospitals (MUH), Mansoura, Egypt


Colon cancer is one of the commonest tumours in the world. Although most colon cancer patients are colonized by adenocarcinoma, some other pathologies such as adenosquamous carcinoma are rarely encountered. We present two patients with right colon adenosquamous carcinoma. Both patients were males and both suffered a nodepositive disease. Furthermore, one of them developed recurrence 7 months after initial radical surgery, despite formal colon adjuvant chemotherapy given. In conclusion, the patients with adenosquamous colon cancer are a subgroup with a worse prognosis, and questionable response to the conventional chemotherapeutic regimens as FOLFOX (flourouracil, leucoverin, and oxaloplatin) and CAPEOX (capecitabine and oxaloplatin).


How to cite this article:

Zuhdy M, Alghandour R, Elhawary M, Metwally IH, Shokeir FA. Adenosquamous carcinoma of the colon: a report of two cases and literature review. Middle East J Cancer. 2023;14(2):327- 31. doi: 10.30476/mejc.2022. 92185.1648.

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