Document Type : Original Article


1 Breast Diseases Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

2 Gynecology Oncology Division, Department of Obstetrics and Gynecology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

3 Maternal-Fetal Medicine Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

4 Core Medical Trainee, Northumbria Healthcare NHS Foundation Trust, Newcastle upon Tyne, U.K.


Background: Hyperthermic intraperitoneal chemotherapy (HIPEC) is increasingly used to treat peritoneal carcinomatosis (PC). The objective was to evaluate the outcomes of cytoreductive surgery (CRS) and HIPEC in our center.
Method: In this retrospective study, data were collected from 43 patients with PC who underwent CRS-HIPEC in 2016 at Faghihi Hospital of Shiraz University of Medical Sciences. Outcomes were collected and analyzed. Analyses were conducted through SPSS 23. P-value < 0.05 was considered to be statistically significant.
Results: The mean age of the patients was 52.23 پ} 11.82 years. The participants in the study analysis consisted of 36 female (83.7%) and seven male patients (16.3%). The most common primary tumor was ovarian cancer (62.8%). Completeness of the cytoreduction score of CC0/CC1 was obtained in 87.7% of the patients. The 1- and 3- year overall survivals were 88% and 60%, respectively.
Conclusion: Our study supports that employing CRS and HIPEC for PC is feasible with acceptable morbidity in our center.


How to cite this article:

Akrami M, Khezri S, Tahmasebi S, Karami MY, Shiravani Z, Zangouri V, et al. Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal surface malignancy: Initial report from Shiraz surgical oncology group. Middle East J Cancer. 2022;13(3):458-65. doi: 10.30476/mejc.2021.87830.1440.

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