Subcutaneous Panniculitis-Like T-Cell Lymphoma in a Patient Receiving Long-Term Panniculitis Treatment: A Case Report

Barut, Saime Gül; Lşik, Cansu Benli

doi:10.30476/mejc.2021.84915.1243

Subcutaneous Panniculitis-Like T-Cell Lymphoma in a Patient Receiving Long-Term Panniculitis Treatment: A Case Report

Document Type : Case Report(s)

Authors

Saime Gül Barut ¹

Cansu Benli lşik ²

¹ Department of Medical Pathology, University of Health Sciences, Haseki Training and Research Hospital, Istanbul, Turkey

² Department of Medical Pathology, University of Health Sciences, Samsun Training and Research Hospital, Samsun, Turkey

https://doi.org/10.30476/mejc.2021.84915.1243

Abstract

Subcutaneous panniculitis-like t-cell lymphoma (SPTL) is known as a rare type of cutaneous lymphoma characterized with penetration of neoplastic T cells to the subcutaneous tissue. It constituates less than 1% of all non-Hodgkin lymphomas.
We described herein a 49-year-old woman with SPTL who presented with redpurple- colored persistent subcutaneous nodules disseminated on trunk and both extremities. The lesions were present for 15 years. She had been diagnosed as panniculitis and her lesions had not regressed with panniculitis treatment. SPTL was diagnosed due to histopathological examination of the lesions that revealed CD3 positive, CD8 positive, CD4 negative and CD56 negative atypical lymphoid infiltration with lobular and septal panniculitis-like pattern.
SPTL must be always kept in mind as a differential diagnosis, while examining biopsies of patients with panniculitis-like lesions resistant to long-term treatment. It is also important to remember that the biopsy material should be in such depth that involves subcutaneous fat tissue.

Keywords

Panniculitis-like lymphoma

Cutaneous

Lymphoma

T-Cell lymphoma

Histopathology

How to cite this article:

Barut SG, Işik CB. Subcutaneous panniculitis-like T-cell lymphoma in a patient receiving long-term panniculitis treatment: A case report. Middle East J Cancer. 2021;12(4):602- 7. doi: 10.30476/mejc.2021. 84915.1243.