Dramatic Response of a Case of Recurrent Basal Cell Carcinoma to Systemic Chemotherapy

Omidvari, Shapour; Nasrolahi, Hamid; Ansari, Mansour; Ahmadloo, Niloofar; Mosalaei, Ahmad; Mohammadianpanah, Mohammad

Dramatic Response of a Case of Recurrent Basal Cell Carcinoma to Systemic Chemotherapy

Document Type : Case Report(s)

Authors

Shapour Omidvari ¹

Hamid Nasrolahi ²

Mansour Ansari ³

Niloofar Ahmadloo ¹

Ahmad Mosalaei ⁴

Mohammad Mohammadianpanah ¹

¹ Associate Professor of Radiation Oncology, Shiraz University of Medical Sciences, Shiraz, Iran

² Radiation Oncologist, Shiraz University of Medical Sciences, Shiraz, Iran

³ Assistant Professor of Radiation Oncology, Shiraz University of Medical Sciences, Shiraz, Iran

⁴ Professor of Radiation Oncology, Shiraz University of Medical Sciences, Cancer Research Center, Shiraz, Iran

Abstract

Basal cell carcinoma (BCC) is the most common cancer among humans, and the standard treatment is surgery. Other modalities are reserved as a second line of treatment. Topical chemotherapy may be used in primary BCC. Systemic chemotherapy has no role in the primary treatment of BCC, although it may be efficacious in metastatic cases. We report the case of a patient with persistent recurrent BCC following multiple surgeries and radiotherapy, who achieved a dramatic response with a cisplatin and 5-flourouracil chemotherapy regimen.