Number of Submissions	2,377
Rejected Submissions	1,281
Rejection Rate	54
Accepted Submissions	819
Acceptance Rate	34

Middle East Journal of Cancer (MEJC) is an international peer-reviewed journal which aims to publish high-quality basic science and clinical research in the field of cancer. This journal will also reflect the current status of research as well as diagnostic and treatment practices in the field of cancer in the Middle East, where cancer is becoming a growing health problem. Lastly, MEJC would like to become a model for regional journals with an international outlook. Accordingly, manuscripts from authors anywhere in the world will be considered for publication. From June 1, 2020, the payment of a processing and publication charges are mandatory (for Iranian authors) for all types of manuscripts sent to the Middle East Journal of Cancer (MEJC).

MEJC is indexed in the Thomson Reuters Web of Science: Emerging Sources Citation Index (ESCI), a new edition of Web of Science™. All articles starting from 2015, will be included in this index.

Middle East Journal of Cancer has now received an impact factor of 0.5

Original Article(s)

Exploring the Apoptotic and Cytotoxic Effects of Thymol in C6 Glioma Cells

Pages 285-296

https://doi.org/10.30476/mejc.2026.106361.2261

Negar Ghazvini, Pejman Hosseinzadeh, Sadaf Afshari, Bahram Bibak, Mahsa Jalali, Ghazale Biglari, Seyed Sajad Ahmadi, Reza Salarinia, Amir R. Afshari

Altered PLAU Expression in Porphyromonas gingivalis-Treated Human Immortalised Oral Epithelial Cells and Its Putative Role in Head and Neck Squamous Cell Carcinoma

Pages 297-311

https://doi.org/10.30476/mejc.2026.106070.2255

Adithyan Kannan, Vijayashree Priyadharsini Jayaseelan

The Role of IGFBP7 in EGFR-TKI Acquired Resistant Lung Cancer

Pages 312-320

https://doi.org/10.30476/mejc.2026.107427.2290

Qiongge Hu, Wenjing Ruan, Huiqi Zhu, Chao Yan, Yiming Xu

Patuletin Caused Growth Inhibition of NCI-H460 Cancer Cells via Induction of Apoptosis

Pages 321-332

https://doi.org/10.30476/mejc.2026.107774.2301

Sana Irshad, Hazar Khan, Asma Khawer, Muhammad Aitmaud Uddolah Khan Khan, Anum Razzak, Mudassar Azhar, Talat Roome, Shaheen Faizi, Ahsana Dar Farooq, Muhammad Kashif

The Inhibitory Effect of Ritanserin (5HT2 Receptor Antagonist) on Growth and Angiogenesis in Model of HT29 Colon Cancer Cells Incubation in Nude Mice

Pages 333-342

https://doi.org/10.30476/mejc.2026.106688.2267

Fatemeh Hosseinzadeh, Ramin Ataee, Esmail Fattahi, Hossein Ghalehnoei

ROCK1 and ROCK2 siRNAs Decrease Proliferation and Increase Apoptosis in Human Head and Neck Squamous Cell Carcinoma

Pages 343-353

https://doi.org/10.30476/mejc.2026.106939.2278

Maedeh Vakili Saatloo, Ahmad Yari Khosroushahi, Yasmin Mohamadzadeh Gharebaghi, Maryam Kouhsoltani

The Prognostic Significance of LVSI in Early-Stage Endometrioid Endometrial Cancer: Insights into Recurrence Patterns and Survival Outcomes

Pages 354-363

https://doi.org/10.30476/mejc.2026.105882.2252

Fatemeh Sadat Najib, Parisa Yazdanshenas, Mojgan Akbarzadeh Jahromi, Zahra Shiravani

Investigating Ovarian Function in Pre-Menopausal Estrogen Receptor-Positive Breast Cancer: A Cross-Sectional Study

Pages 364-371

https://doi.org/10.30476/mejc.2026.106922.2276

Afsaneh Kheirmand Parizi, Amirreza Nejadheidari, Naeem Nikpour, Fatemeh Nejadheidari

Case Report(s)

Rare Extrapulmonary Metastases from Thigh Myxoid Liposarcoma: Two Case Reports and Literature Review

Pages 372-378

https://doi.org/10.30476/mejc.2026.107131.2283

Engy Elemry, Khalid Atallah, Ahmed Hassan, Ahmed Sameh, Shaimaa M Yussif, Mohamed Elhawary, Shadi Awny, Mohammad Zuhdy

Post-Radiation Vaginal Angiosarcoma: A Case Report

Pages 379-384

https://doi.org/10.30476/mejc.2026.106736.2268

Fatemeh Nili, Sara Parviz, Amirmohsen Jalaeefar, Seyedeh Zahra Mousavi, Nastaran Tayebi

Calendar of Events

Calendar of Events (October 2026)

Pages 385-385

Acknowledgment to Reviewers

Acknowledgment to Reviewers (2026)

Review Article(s)

Monoclonal Antibodies in the Treatment of Small Cell Lung Cancer: A Review of Clinical Trials

Articles in Press, Accepted Manuscript, Available Online from 01 January 2027

https://doi.org/10.30476/mejc.2026.109133.2355

Ali Asghar Hemmati, Soroush Alaei

A Narrative Review on Targeting Neurokinin-1 Receptor (NK1R) System: A New Strategy for Breast Cancer Treatment

Articles in Press, Accepted Manuscript, Available Online from 01 January 2027

https://doi.org/10.30476/mejc.2026.109106.2353

Zahra Aalipour Hafshejani, Morteza Yousefi Darani, Mohammad Aghebati, Alireza Shirzadi

Original Article(s)

Bioinformatics Analysis and Experimental Assessment of RHEX and IKBKE in Endometrial Cancer

Articles in Press, Accepted Manuscript, Available Online from 01 January 2027

https://doi.org/10.30476/mejc.2025.109375.2367

Zohreh Koohini, Mohammad Reza Haghshenas, Ahmad Tahmasebi, Zahra Shiravani, Fatemeh Sadat Najib, Maryam Aghdaki, Mahintaj Dara, Nafiseh Maghsoodi, Amin Ramezani, Abbas Ghaderi

Association of Dietary Patterns and the Odds of Colorectal Cancer in a Sample of the Population in Southern Iran: An Observational Case-Control Study

Articles in Press, Accepted Manuscript, Available Online from 01 January 2027

https://doi.org/10.30476/mejc.2026.110553.2401

Mohsen Mohit, Sayedeh Zahra Hosseini, Mohammadreza Ravanbod, Seyed Vahid Hosseini, Najmeh Hejazi

Impact of MRI Findings and Clinical Parameters on Predicting Tumor-Infiltrating Lymphocytes in Hepatocellular Carcinoma Patients

Articles in Press, Accepted Manuscript, Available Online from 01 April 2027

https://doi.org/10.30476/mejc.2026.110435.2398

Yaser Arafat, Amrallah Mohammed, Ahmad Barakat Waley, Basma Soliman K, Mohamed S. Bayomi, Amira Hanna, Basant EL-Shafaay, Marwa M. EL- Mosely, Doaa Mandour

Integrated in Silico Analysis Reveals miR-551b-3p as a Potential Tumor Suppressor and Prognostic Biomarker in Breast Cancer

Articles in Press, Accepted Manuscript, Available Online from 01 January 2027

https://doi.org/10.30476/mejc.2026.110333.2395

Kübra Su Eda ÇELENK, Esen ÇAKMAK

Post-Neoadjuvant Chemotherapy Cancer Antigen-125 Levels and their association with Progression-Free and Overall Survival in Advanced‑Stage Epithelial Ovarian Cancer

Articles in Press, Accepted Manuscript, Available Online from 01 January 2027

https://doi.org/10.30476/mejc.2026.106949.2277

Fatemesadat Najib, Zahra Shiravani, Maryam Khoshdel, Maryam Aghdaki

Merkel Cell Carcinoma of the Skin: An Exceptionally Rare Entity with Unique Locality-Related Characteristics

Articles in Press, Accepted Manuscript, Available Online from 01 April 2027

https://doi.org/10.30476/mejc.2026.110574.2402

Omar Hamdy, Rehab T Eldesouky, Ahmed S Elsaid, Elissia F Gerges, Eyad M Elsakti, Kareem K Belal, Mohamed Elbadrawy

The Impact of HIF-1α and LDHA Inhibition on the Expression of Autophagy and Glucose Metabolism Pathway Genes in HL 60 and K562 Cell Lines

Articles in Press, Accepted Manuscript, Available Online from 01 April 2027

https://doi.org/10.30476/mejc.2026.110670.2407

mehrshad shams, tamana eskandari, amirmohammad roshanfekr, amir kahrizi, hossein asgarian-omran, reza valadan, mohsen tehrani, saeid taghiloo

A Comparative Study of Moderately and Well-Differentiated Oral Squamous Cell Carcinoma: Clinicopathological, Immunohistochemical analysis and Quality of Life Outcomes

Articles in Press, Accepted Manuscript, Available Online from 01 April 2027

https://doi.org/10.30476/mejc.2026.110691.2408

Divyashree Sankar, Gheena Sukumaran

Genetic Variants of Human Organic Cation Transporter1 (hOCT1) -M408V and M420del- Are Not Associated with Imatinib Response in Chronic Myeloid Leukemia

Articles in Press, Accepted Manuscript, Available Online from 01 April 2027

https://doi.org/10.30476/mejc.2026.110821.2414

Nesma Elshahat, Sahar Kamal, Somaia Mohamed Mousa, Hend Nabil Ellithy, Shirihan Mahmoud Mahgoub, Mohamed Fateen

HO-3867 Induces Cell Apoptosis by Reducing STAT3 Signaling in Hepatocellular Carcinoma

Articles in Press, Accepted Manuscript, Available Online from 01 April 2027

https://doi.org/10.30476/mejc.2026.107082.2282

Zhiya Xiao, Jun Hu

Fatty Acid Synthetase and its Role in the Pathological Response after Neoadjuvant Chemotherapy in Triple-Negative Breast Cancer

Articles in Press, Accepted Manuscript, Available Online from 01 April 2027

https://doi.org/10.30476/mejc.2026.111880.2437

Yaser Arafat, Amrallah Mohammed, Israi Mahgoub, Mohamed Biomy, Doa Mandour, Waley Ahmad, Adel Bakrey

The Expression of Long Non-Coding RNA BACE1-AS and SIRT1 gene in Peripheral Blood Leukocytes of Breast Cancer Patients: A Computational and Molecular Study

Articles in Press, Accepted Manuscript, Available Online from 06 October 2026

https://doi.org/10.30476/mejc.2026.111535.2430

Hadis Musavi, Fereshteh Ahmadipour, Tayebeh Azramezani Kopi, Zahra Yazdani, Fatemeh Gorjinezhad, Fariba Ghodrati, Abouzar Bagheri, Masoumeh Karimi, Abbas Khonakdar-Tarsi