Shiraz University of Medical Sciences
Middle East Journal of Cancer
2008-6709
1
4
2010
10
01
Good Writing and Good Reporting to Enhance the Impact of Articles and Journals
151
153
41899
EN
Karen
Shashok
Co-coordinator, AuthorAID in the Eastern Mediterranean, Granada, Spain and Shiraz, Iran
Journal Article
2013
10
02
Shiraz University of Medical Sciences
Middle East Journal of Cancer
2008-6709
1
4
2010
10
01
Combined Methylene Blue Dye and Radioactive Tracer Technique for Sentinel Lymph Node Localization in Early Breast Cancer
155
158
41898
EN
Sedigheh
Tahmasebi
General Surgery Department, Shiraz University of Medical Sciences, Shiraz, Iran
0000-0001-5880-2063
Mohammad
Haghighifard
General Surgery Department, Shiraz University of Medical Sciences, Shiraz, Iran
Abdolrasoul
Talei
General Surgery Department, Shiraz University of Medical Sciences, Shiraz, Iran
0000-0001-9111-3681
Journal Article
2013
10
02
Background: Sentinel lymph node biopsy is a technique used to identify the axillary node most likely to contain tumor cells that have metastasized from a primary carcinoma of the breast. This technique provides accurate staging with fewer complications than axillary dissection and may result in decreased costs. We designed the present study to determine the accuracy and success rate of a combined blue dye and radioactive tracer technique in sentinel node localization.Methods: This prospective study included 70 patients with early stage (tumor>5 cm; T1, T2) operable breast cancer and nonpalpable axillary lymphadenopathy seen between 2005 and 2009. Patients underwent sentinel lymph node localization using 4 mL of blue dye combined with radioactive colloid. After identification and removal of the sentinel node(s), the axilla was checked for any residual radioactivity. A sentinel node was defined as any node that was hot, hot and blue or only blue.Results:The sentinel node was identified in 66 patients with a detection rate of 94.2%, and a mean of 1.5 sentinel nodes were identified and harvested (range of 1-4). In 23 cases, the sentinel lymph node contained metastatic disease on pathological assessment. There was no pathological evidence of any metastases in the sentinel node in the remaining 43 patients. All sentinel lymph nodes were located in level I of the axillary region. In four patients, no sentinel lymph node was found, so axillary dissection was performed. The sensitivity of the procedure in predicting further axillary disease was 95.6% with a specificity of 97.6%.Conclusion: The present study describes the blue dye and radioisotope localization technique as successful in identifying the sentinel lymph node in early-stage breast cancer patients.
Shiraz University of Medical Sciences
Middle East Journal of Cancer
2008-6709
1
4
2010
10
01
Awareness and Knowledge of Breast Cancer Among University Students in Al Madina Al Munawara Region
159
166
41901
EN
Fawzia
Habib
Department of Obstetrics and Gynecology, College of Medicine, Taibah University,
Al Madina Al Munawara, Kingdom of Saudi Arabia
Shaista
Salman
Department of Radiology, College of Medicine, Taibah University, Al Madina Al Munawara, Kingdom of Saudi Arabia
Maha
Safwat
Department of Anatomy, College of Medicine, Taibah University, Al Madina Al Munawara, Kingdom of Saudi Arabia
Sherien
Shalaby
Department of Pediatrics, College of Medicine, Taibah University, Al Madina Al Munawara, Kingdom of Saudi Arabia
Journal Article
2013
10
02
Background: Breast cancer, a critical health problem, is considered to be a progressive disease with a poor prognosis if detected late. Public education about the disease plays a pivotal role in early detection and subsequent improvements in prognosis. The present study assesses the knowledge and awareness about various aspects of breast cancer among female university students.Methods: The knowledge of various aspects of breast cancer including incidence, early warning signs, risk factors, screening, early detection measures and sources of information was evaluated among female students in different faculties of Taibah University, Al Madina Al Munawara, Saudi Arabia, from December 1 to 31, 2008. A self-structured validated questionnaire that contained 23 itemized questions about breast cancer was randomly distributed to the participants. Respondents’ levels of knowledge were determined and transferred to electronic spreadsheets for further analysis.Results: Of 301 students, 247 (82%) were available for final analysis with a mean age of 27 years (SD 12.1; age range: 18 to 39 years). Two hundred eleven (85.4%) respondents were single, 218 (88%) nulliparous and 213 (86%) had no family history of breast cancer. Their knowledge about the incidence of the disease was poor; only 34% replied correctly. A total of 148 (59.9%) respondents mentioned swelling in the skin/axilla while 123 (49.7%) suggested skin changes as early warning signs of breast cancer. None of the participants expressed knowledge about all established risk factors of the disease. One hundred fifty-nine (64.4%) did not know the proper way to perform a breast self-examination and 104 (42.2%) had never performed this test. Additionally, 128 (51.8%) knew that mammography was a screening tool for breast cancer. Sources of information about the disease were: television and radio (139, 56.2%), printed material in journals and newspapers (86, 34.8%) and family physicians (13, 15.2%).Conclusion: This study revealed that respondents showed deficient knowledge about key issues concerning breast cancer and its early detection measures. It also revealed that health workers were not the main source of information in the community, thereby posing a challenge for community health services to provide basic required information about breast cancer.
Shiraz University of Medical Sciences
Middle East Journal of Cancer
2008-6709
1
4
2010
10
01
Comparison of Prostate and Bladder Volume Measurements from MRI and Pre- and Post-MRI Ultrasound Images
167
173
41902
EN
Milad
Baradaran-Ghahfarokhi
Medical Physics and Medical Engineering Department, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
Mohammad Hadi
Bagheri
Medical Imaging Research Center and Department of Radiology, Shiraz University of Medical Sciences, Shiraz, Iran
Mehrzad
Lotfi
Medical Imaging Research Center and Department of Radiology, Shiraz University of Medical Sciences, Shiraz, Iran
Mohammad Amin
Mosleh-Shirazi
Center for Research in Medical Physics and Biomedical Engineering and Radiotherapy Department, Shiraz University of Medical Sciences, Shiraz, Iran
Reza
Faghihi
Medical Radiation Department, School of Mechanical Engineering, Shiraz University, Shiraz, Iran
Kamal
Hadad
Medical Radiation Department, School of Mechanical Engineering, Shiraz University, Shiraz, Iran
Sedigheh
Sina
Medical Radiation Department, School of Mechanical Engineering, Shiraz University, Shiraz, Iran
Journal Article
2013
10
02
Background: Safe dose escalation is highly desirable in radiotherapy for prostate cancer. Prostate displacement due to bladder filling can be significant, so improved targeting of the prostate by ultrasound imaging potentially allows for a reduction in the target margin and consequently less toxicity. This study estimates the accuracy of ultrasound for prostate and bladder volume measurements by comparing ultrasound images taken immediately before and after magnetic resonance imaging to reduce the effect of organ filling on measurement accuracy.Methods: Three patients with a wide range of prostate sizes underwent pelvic magnetic resonance imaging and ultrasound imaging. We tested the correlation between the two measurements and the differences between the ultrasound measurements before and after magnetic resonance imaging using statistical analysis.Results: Based on a total number of 18 volume measurements, a strong linear correlation was found (r=0.95), but there were no significant differences between ultrasound imaging performed before and after magnetic resonance imaging (P=0.809).Conclusion: Our results provide additional evidence that ultrasound imaging measures bladder and prostate volumes in a reproducible and accurate manner over a wide range of volumes, which enables its use with different fractions of prostate radiotherapy.
Shiraz University of Medical Sciences
Middle East Journal of Cancer
2008-6709
1
4
2010
10
01
Saudi Cancer Patients’ Attitudes towards Disclosure of Cancer Information
175
180
41896
EN
Ali M.
Al-Amri
Department of Internal Medicine and Oncology, College of Medicine, University of Dammam, King Fahd University Hospital, Al-Khobar, Eastern Province, Kingdom of Saudi Arabia
Journal Article
2013
10
02
Background: The aim of this study was to explore Saudi cancer patients' views regarding cancer information disclosure and whether differences existed between regions or gender.Methods: In this cross-sectional questionnaire-based prospective survey, we interviewed 332 Saudi cancer patients who received oncological care at King Fahd University Hospital, Al-Khobar, Saudi Arabia from July 2002 to July 2009 to explore their attitudes regarding disclosure of cancer information.Results: The vast majority of Saudi cancer patients wanted to know the diagnosis of cancer (98%) and only 2% wanted the information to remain undisclosed. Seventy percent of the women wanted family members to know compared to only 39% of the men (P<0.001). Only 10% of the patients wanted their friends to know. In this study, 99% and 98%, respectively, wanted to know about the benefits of therapy and about their diagnosis of cancer. Of both genders, 98% also wanted to know the side effects of therapy and the prognosis. The attitudes of Saudi men and women with cancer were almost identical apart from sharing information with their family members. 99% of eastern region cancer patients wanted the diagnosis of cancer disclosed compared to 74% of those from other regions (P=0.04).Conclusion: The findings of this study indicated that most Saudi cancer patients wanted disclosure of cancer information. Significantly more women than men wanted to share information with their family. More Eastern region patients wanted to know about their diagnosis of cancer compared to patients from other regions.
Shiraz University of Medical Sciences
Middle East Journal of Cancer
2008-6709
1
4
2010
10
01
Dramatic Response of a Case of Recurrent Basal Cell Carcinoma to Systemic Chemotherapy
181
184
41895
EN
Shapour
Omidvari
Associate Professor of Radiation Oncology, Shiraz University of Medical Sciences, Shiraz, Iran
0000-0003-3656-9891
Hamid
Nasrolahi
Radiation Oncologist, Shiraz University of Medical Sciences, Shiraz, Iran
Mansour
Ansari
Assistant Professor of Radiation Oncology, Shiraz University of Medical Sciences,
Shiraz, Iran
0000-0002-8249-1776
Niloofar
Ahmadloo
Associate Professor of Radiation Oncology, Shiraz University of Medical Sciences, Shiraz, Iran
0000-0003-3178-8577
Ahmad
Mosalaei
Professor of Radiation Oncology, Shiraz University of Medical Sciences,
Cancer Research Center, Shiraz, Iran
0000-0002-3986-8865
Mohammad
Mohammadianpanah
Associate Professor of Radiation Oncology, Shiraz University of Medical Sciences, Shiraz, Iran
0000-0001-9391-8977
Journal Article
2013
10
02
Basal cell carcinoma (BCC) is the most common cancer among humans, and the standard treatment is surgery. Other modalities are reserved as a second line of treatment. Topical chemotherapy may be used in primary BCC. Systemic chemotherapy has no role in the primary treatment of BCC, although it may be efficacious in metastatic cases. We report the case of a patient with persistent recurrent BCC following multiple surgeries and radiotherapy, who achieved a dramatic response with a cisplatin and 5-flourouracil chemotherapy regimen.
Shiraz University of Medical Sciences
Middle East Journal of Cancer
2008-6709
1
4
2010
10
01
Bony Calvarium as the Sole Site of Metastases in Squamous Cell Carcinoma of the Uterine Cervix
185
188
41900
EN
Niloofar
Ahmadloo
Radiation Oncology Department, Shiraz University of Medical Sciences, Shiraz, Iran
0000-0003-3178-8577
Farzad
Bidouei
Radiation Oncology Department, Shiraz University of Medical Sciences, Shiraz, Iran
Shapour
Omidvari
Radiation Oncology Department, Shiraz University of Medical Sciences, Shiraz, Iran
0000-0003-3656-9891
Mansour
Ansrai
Radiation Oncology Department, Shiraz University of Medical Sciences, Shiraz, Iran
Ahmad
Mosalaei
Radiation Oncology Department, Shiraz University of Medical Sciences, Shiraz, Iran
0000-0002-3986-8865
Mohammad
Mohammadianpanah
Radiation Oncology Department, Shiraz University of Medical Sciences, Shiraz, Iran
0000-0001-9391-8977
Journal Article
2013
10
02
Isolated skeletal metastasis to the bony calvarium is extremely rare in patients with squamous cell carcinoma of the uterine cervix. We describe the clinical and imaging findings in a case of squamous cell carcinoma of the uterine cervix with metastases to the bony calvarium as the sole site of metastasis. The patient was a 65-year-old woman with squamous cell carcinoma of the uterine cervix, FIGO stage IIIb, whose initial treatement was chemoradiation therapy. After 22 sessions of external-beam radiation, she developed headaches. On physical examination she had skull bone tenderness. On plain skull X-ray, there were osteolytic bony lesions. Brain MRI showed multiple enhancing skull bone metatstses. Eventually, a whole body bone scintigraphy revealed isolated diffuse increased activity in the bony calvarium. In the literature review, we found only three similar cases of cervical cancer with scalp metastases and involvement of the bony calvarium.
Shiraz University of Medical Sciences
Middle East Journal of Cancer
2008-6709
1
4
2010
10
01
Pseudoneutropenia from EDTA Leukoagglutination
189
190
41897
EN
Arafat
Tfayli
Division of Hematology/Oncology, American University of Beirut, Beirut, Lebanon
Laxmi
Gadde
Department of Internal Medicine, Oklahoma University Health Sciences Center,
Oklahoma City, Oklahoma, USA
Ali
Shamseddin
Division of Hematology/Oncology, American University of Beirut, Beirut, Lebanon
Journal Article
2013
10
02