@article { author = {Mohamad Zaki, Aznida Zaki and Abd Rahim, Muhammad Aklil and Zaidun, Zuraidah and Ramdzan, Abdul Rahman and Md Isa, Zaleha}, title = {Exposure to Non-Ionizing Radiation and Childhood Cancer: A Meta-Analysis}, journal = {Middle East Journal of Cancer}, volume = {11}, number = {1}, pages = {1-11}, year = {2020}, publisher = {Shiraz University of Medical Sciences}, issn = {2008-6709}, eissn = {2008-6687}, doi = {10.30476/mejc.2019.78705.0}, abstract = {Background: A slight increase in the childhood cancer trend has been observed for the past few decades. Non-ionizing radiation is one of the environmental factors linked to childhood cancers. This review is conducted to assess the association between non-ionizing radiation and childhood cancer based on all original studies to date. Methods: A systematic search was conducted on the titles and abstracts pertaining to non-ionizing radiation and childhood cancers using the PubMed, Scopus, SAGE and ScienceDirect databases from inception up to November 2018. Quality of each article was appraised using the Newcastle-Ottawa Scale, meta-analysis was performed with Review Manager, and fixed effects were used to estimate the pooled OR of the selected studies. Results: A total of 15 articles met all the selection criteria. Twelve articles were included in the meta-analysis. Pooled risk estimates of the 12 studies, obtained via fixed effects model, showed that children exposed to 0.2 μT or more of EMF non-ionizing radiation run 1.33 times higher risks of contracting childhood cancer compared to those with less than 0.2 μT exposure (95% CI: 1.10, 1.60). The studies were statistically homogeneous (chi-squared P=0.71, I2=0%), and there was no evidence of publication bias. Conclusion: It cannot be concluded that children exposed to non-ionizing radiation have higher risks of childhood cancer compared to those who were not exposed as claimed by the previous reviews. However, concerns about non-ionizing radiation exposure and childhood cancer should not be neglected.}, keywords = {Non-Ionizing Radiation,Childhood cancer,Electromagnetic Fields,Meta-analysis}, url = {https://mejc.sums.ac.ir/article_45947.html}, eprint = {https://mejc.sums.ac.ir/article_45947_6f731cc63cbc91b819a9e986832be6c0.pdf} }