@article { author = {Shabbir-Moosajee, Munira and Mohyuddin, Ghulam and Khan, Sara and Kamal, Ayeesha}, title = {Acute Acquired Demyelinating Polyneuropathy:An Initial Presentation of Diffuse Large B Cell Lymphoma}, journal = {Middle East Journal of Cancer}, volume = {4}, number = {1}, pages = {35-38}, year = {2013}, publisher = {Shiraz University of Medical Sciences}, issn = {2008-6709}, eissn = {2008-6687}, doi = {}, abstract = {Neurological signs and symptoms are commonly associated with both Hodgkin’s and non-Hodgkin’s lymphoma and are mostly attributed to either direct lymphomatous involvement of the nervous system, either as a result of extension to the spinal cord or nerves, or due to infiltration by lymphoma cells and drug toxicity. Guillain-Barre syndrome and its variants have been reported very infrequently in the literature. We present the case of a 70-year-old male admitted to the hospital for evaluation of uncontrolled hypertension. Incidentally, he was noted to have a low platelet count and a leukoerythroblastic picture in the peripheral blood. Two days into admission, he developed bilateral symmetrical ascending paresis consistent with acute acquired demyelinating polyneuropathy, a common variant of Guillain-Barre syndrome. At about the same time he developed worsening cytopenia and was diagnosed with diffuse large B cell lymphoma according to a bone marrow biopsy. The patient was treated with intravenous immunoglobulin for Guillain-Barre syndrome with significant improvement in muscle strength and subsequently treated with chemotherapy for his lymphoma.}, keywords = {}, url = {https://mejc.sums.ac.ir/article_41846.html}, eprint = {https://mejc.sums.ac.ir/article_41846_b9378c7ace55509b0e713b451483415c.pdf} }