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0.05).Conclusion: Administration of 8 mg of dexamethasone an hour prior to irradiation for the treatment period and three days afterwards is effective in significantly decreasing the incidence of pain flare. Dexamethasone is well tolerated and may be recommended for all adult patients who undergo palliative bone irradiation who have no contraindi- cation to this treatment. Larger phase 3 randomized trials are needed to confirm these findings.]]>
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